Research progress on the relationship between fibroblast growth factor 21 and vascular calcification

doi:10.3877/cma.j.issn.2095-3216.2022.04.009

Abstract

Abstract:

Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor family, which has biological effects such as lipid-lowering, anti-inflammation and anti-oxidation. In recent years, studies have found that FGF21 can effectively inhibit vascular calcification and reduce the occurrence of cardiovascular events. So, it has been regarded as a new protective factor for the cardiovascular system, and is expected to become a new clinical target for the prevention and treatment of vascular calcification. This article reviewed the latest research progress on the relationship between FGF21 and vascular calcification.

Key words: Fibroblast growth factor 21, Vascular calcification, Vascular smooth muscle cells

Qingling Xia, Santao Ou. Research progress on the relationship between fibroblast growth factor 21 and vascular calcification[J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2022, 11(04): 231-234.

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